Open AccessEffects of dexmedetomidine on cognitive function in elderly patients after laparoscopic cholecystectomy
Author(s) -
Na Li,
Lei Xiong,
Yehua Wu,
Xiaojian Chen,
Ya-Zhen Meng,
Shuang-Feng Li,
Yi Xiong
Publication year - 2020
Publication title -
medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.59
H-Index - 148
eISSN - 1536-5964
pISSN - 0025-7974
DOI - 10.1097/md.0000000000020177
Subject(s) - dexmedetomidine , medicine , cinahl , psycinfo , medline , cochrane library , scopus , meta analysis , cognition , surgery , psychiatry , sedation , political science , psychological intervention , law
Background: Although many studies have reported the effects of dexmedetomidine on cognitive function (CF) in elderly patients after laparoscopic cholecystectomy (LCT), to this date, its effects are still not well understood. The aim of this study is to produce a qualitative synthesis of assessing the effects of dexmedetomidine on CF in elderly patients after LCT. Methods: We will conduct a comprehensive search in Cochrane Library, MEDLINE, EMBASE, CINAHL, PsycINFO, Scopus, VIP Database, WANGFANG Database, Chinese Biomedical Literature Database, and China National Knowledge Infrastructure from the commencement to March 31, 2020 without restrictions of language and publication status. In addition, we will also search grey literature, including conference abstracts, dissertations, reference lists of included studies and relevant reviews. All potential studies will be identified independently by 2 authors to determine their inclusion against previously defined eligibility criteria. The quality of selected papers will be assessed using Cochrane risk of bias tool. All statistical analysis will be performed using RevMan 5.3 software. Results: This study will provide a synthesis of the current available data on assessing the effects of dexmedetomidine on CF in elderly patients after LCT. Conclusions: Its findings will provide qualitative evidence to better understand the effects of dexmedetomidine on CF in elderly patients after LCT. INPLASY Registration Number: INPLASY202040030.