Open AccessChinese herbal medicine for premature ovarian insufficiency
Author(s) -
Yifeng Shao,
Zhou Hu-ihao,
Meng Zhou,
Pian Ying,
Yao Zhitao,
Xin Jiang
Publication year - 2020
Publication title -
medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.59
H-Index - 148
eISSN - 1536-5964
pISSN - 0025-7974
DOI - 10.1097/md.0000000000019371
Subject(s) - medicine , premature ovarian insufficiency , cochrane library , medline , data extraction , traditional chinese medicine , randomized controlled trial , traditional medicine , alternative medicine , family medicine , intensive care medicine , pathology , political science , law
Background: Premature ovarian insufficiency (POI) is the loss of function of the ovaries before age 40. Chinese herbal medicine (CHM) has been treating POI for long time. Therefore, we conduct this study to assess the efficacy and safety of CHM for POI. Methods: Seven databases will be searched from inception to December 31, 2018: PubMed, Embase, Cochrane Library, Chinese National Knowledge Infrastructure (CNKI), China Biology Medicine disc (CBM), WanFang Database, and Chongqing Chinese Scientific Journal Database (CQVIP). Randomized controlled trials that used CHM will be included. Two reviewers will independently complete the study selection, data extraction, and study quality assessment according to Cochrane Collaboration. All the data will be analyzed using Review Manage 5.3 software. Results: This study will generate a comprehensive summary on effectiveness and safety of CHM for POI. Conclusion: This study may be beneficial to health policymakers, clinicians, and patients with regard to the use of CHM in POI treatment. Trial registration number: PROSPERO CRD 42019144629.