Open AccessEffect of sustained inflations and intermittent positive pressure ventilation on bronchopulmonary dysplasia or death among neonatal
Author(s) -
Yue Guo,
Yan Jiang,
Hanbo Tang,
Wenjuan Fan,
Chenchen Ai,
Ping Liu
Publication year - 2020
Publication title -
medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.59
H-Index - 148
eISSN - 1536-5964
pISSN - 0025-7974
DOI - 10.1097/md.0000000000019084
Subject(s) - medicine , bronchopulmonary dysplasia , meta analysis , randomized controlled trial , intermittent positive pressure ventilation , cochrane library , confidence interval , psychological intervention , ventilation (architecture) , mechanical ventilation , medline , relative risk , anesthesia , pediatrics , intensive care medicine , gestational age , surgery , pregnancy , mechanical engineering , genetics , psychiatry , political science , law , engineering , biology
Background: Sustained Inflations (SI) and Intermittent Positive Pressure Ventilation (IPPV) are two interventions to prevent Bronchopulmonary dysplasia (BPD). The aim of this study is to assess the effect of these two interventions. Methods: The databases of PubMed, EMBASE, and Cochrane Central Register of Controlled Trials (CENTRAL) will be comprehensively searched from inception to September 2019. All RCTs and quasi-RCTs which compare the efficacy of SI vs IPPV among preterm infants are eligible. We will assess the methodological quality using the Cochrane Handbook version 5.1.0. A meta-analysis will be performed using RevMan 5.3 software and the results will be presented using risk ratios (RRs) and 95% confidence intervals (CIs). Conclusions: This study will provide strong evidence for assessing the effect of SI and IPPV on BPD or death among preterm infants. PROSPERO registration number: CRD42019135816.