Open AccessRadiotherapy with apatinib for recurrence of malignant phyllodes tumor of the breast
Author(s) -
Hong Wu,
Lei Li,
Jing Yang,
Chao Guo,
Weimin Zhang,
Hui Wang
Publication year - 2020
Publication title -
medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.59
H-Index - 148
eISSN - 1536-5964
pISSN - 0025-7974
DOI - 10.1097/md.0000000000018808
Subject(s) - medicine , apatinib , phyllodes tumor , radiation therapy , radiology , surgery , chemotherapy
Rationale: Malignant phyllodes tumors of the breast are rare, and there are currently no guidelines and a large number of clinical trials to guide the treatment of recurrence tumor. Here we reported a case of radiotherapy with apatinib for the treatment of recurrent malignant phyllodes tumor of the breast. Patient concerns: A 58-year-old patient with massive breast mass was admitted to our hospital. Two months after surgical treatment, the tumor recurred in the chest wall scar. Diagnoses: The histopathologic diagnoses was right breast malignant phyllodes tumor with chondrosarcomas and osteosarcomas in some areas. Interventions: The patient was first treated with surgery. Malignant phyllodes tumor recurred in the chest wall two months after surgery and was treated with radiotherapy and apatinib. Outcomes: With surgery, radiotherapy and apatinib treatment, the patient still died within several months. Lessons: Apatinib and radiotherapy failed to obtain good therapeutic effect in the recurrence of breast malignant phyllodes tumor in this case.