Open AccessRosai–Dorfman disease manifesting as epibulbar and orbital tumor
Author(s) -
Qing Huang,
Hong Cai,
Weimin He
Publication year - 2020
Publication title -
medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.59
H-Index - 148
eISSN - 1536-5964
pISSN - 0025-7974
DOI - 10.1097/md.0000000000018757
Subject(s) - medicine , rosai–dorfman disease , diplopia , histiocytosis , presentation (obstetrics) , orbital diseases , radiology , exophthalmos , surgery , lesion , disease , computed tomography , pathology , computed tomographic
Rationale: Rosai-Dorfman disease (RDD) is a rare nonmalignant cell histiocytosis. Here, we report a rare, unusual clinical presentation of epibulbar and orbital tumor as a manifestation of RDD. We also review the literatures on clinical cases of orbital RDD. Patient concerns: A 44-year-old Chinese male was admitted with a 3-month history of eye redness, subconjunctival mass, and diplopia. Diagnosis: An initial diagnosis of epibulbar and orbital tumor was made according to the clinical symptoms, signs, and pre-operative contrast-enhanced computerized tomography results. Interventions: The mass was completely resected and pathology confirmed the RDD diagnosis. The patient received steroids after surgery. Outcomes: The patient recovered well on 18-month follow-up. Conclusion: This appears to be the first report of RDD manifesting as epibulbar and orbital tumor. Pre-operative diagnosis of RDD remains challenging. When the lesion causes diplopia, surgical resection is the most effective treatment.