Open AccessDigital clubbing occurring in intrathoracic Hodgkin lymphoma
Author(s) -
Xiaoyan Gai,
Wei Tse Yang,
Hong Zhu,
Yongchang Sun
Publication year - 2019
Publication title -
medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.59
H-Index - 148
eISSN - 1536-5964
pISSN - 0025-7974
DOI - 10.1097/md.0000000000018388
Subject(s) - medicine , lymphoma , malignancy , radiology , biopsy
Rationale: Digital clubbing is rarely associated with lymphoma. This study reports a case of intrathoracic Hodgkin lymphoma with digital clubbing and reviews the current literature regarding the clinical characteristics of this condition. Patient concern: A 21-year-old woman presented with a 3-month history of cough and 1 month of fever, with apparent digital clubbing. A computed tomography (CT) scan of the lungs revealed a large pulmonary mass. Diagnosis: A CT-guided transthoracic needle biopsy was conducted. Pathology determined a diagnosis of Hodgkin lymphoma. Interventions: The patient underwent 6 courses of chemotherapy and intensification, followed by autografting. Outcomes: The patient recovered and a complete hematological remission was obtained. The patient is alive with no evidence of disease 60 months after diagnosis, with the digital clubbing of the fingers and toes completely resolved. Conclusion: Patients with digital clubbing and intrathoracic lesions need to be examined carefully to determine tumor malignancy.