Open AccessThe efficacy, safety, and cost benefits of splints for fractures of the distal radius in children
Author(s) -
Xin Cui,
Long Liang,
Xu Wei,
Xing Liao,
Yongyao Li,
Hao Cheng,
Yan-Ming Xie,
Yong Cheng,
Yumin Du,
Guangwei Liu,
Hongyan Zhang,
Shiheng Wang,
Jiani Liu,
Zhen Wang,
Yue Zhang,
Yaliang Tian
Publication year - 2019
Publication title -
medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.59
H-Index - 148
eISSN - 1536-5964
pISSN - 0025-7974
DOI - 10.1097/md.0000000000016562
Subject(s) - medicine , splints , cochrane library , randomized controlled trial , meta analysis , medline , evidence based medicine , grading (engineering) , deformity , physical therapy , surgery , alternative medicine , civil engineering , pathology , political science , law , engineering
Background: Distal radius fractures (DRFs) is one of the most common bone injuries in children, which may lead to deformity and other complications if the treatment is not prompt or appropriate. Splints external fixation is a common conservative treatment for such fractures. Therefore, we conducted a systematic review and meta-analysis to explore the efficacy, safety and cost benefits of splints in the treatment of DRFs in children. Methods: PubMed, Web of Science, Embase, Cochrane Library, Cochrane Central Register of Controlled Trials (CENTRAL), and ClinicalTrials.gov, Chinese National Knowledge Infrastructure Database (CNKI), Wanfang Database, and VIP Database were searched for eligible randomized controlled trials (RCTs). The methodological quality of the included studies and the level of evidence for results were assessed, respectively, using the risk bias assessment tool of Cochrane and the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) method. Statistical analysis was conducted with Revman 5.3. Results: This study will analyze and integrate the existing evidence for effectiveness, safety and cost benefits of splints on DRFs in children. Conclusion: The conclusion of this study will provide evidence to effectiveness, safety and cost benefits of splints on DRFs in children, which can further guide the selection of appropriate interventions. PROSPERO registration number: CRD42019123429