Open AccessPost-traumatic stress disorder in living donors after pediatric liver transplantation
Author(s) -
Yimao Zhang,
Junxiang Wang,
Shuguang Jin,
Bo Xiang,
Jing Yang,
Kewei Li,
Bing Huang,
Lai Wei,
Lü-Nan Yan,
Jichun Zhao
Publication year - 2019
Publication title -
medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.59
H-Index - 148
eISSN - 1536-5964
pISSN - 0025-7974
DOI - 10.1097/md.0000000000015565
Subject(s) - medicine , quality of life (healthcare) , vitality , univariate analysis , mental health , cross sectional study , transplantation , liver transplantation , medical record , psychiatry , clinical psychology , multivariate analysis , pathology , philosophy , nursing , theology
Liver transplantation can lead to post-traumatic stress disorder (PTSD) in recipients, but the risk factors associated with PTSD in living donors are unknown. To investigate this progression in pediatric living donors, a cross-sectional investigation was carried out. All participants completed 2 questionnaires: a PTSD self-rating scale (PTSD-SS) and a validated Chinese version of the Medical Outcomes Study Short Form-36 (SF-36). Clinical and demographic data were collected from medical records and self-report questionnaires. Univariate analysis was conducted to identify statistical differences. The prevalence of full PTSD (all symptom clusters) and partial PTSD (2 out of 3 symptom clusters) was 12.1% and 31.1%, respectively. Those with an educational status of elementary school ( P = .001), who were donors to their children ( P = .008), who were in the first 6 months after transplant ( P < .001), or were involved in transplants where the recipients had severe complications ( P = .02) were more likely to have higher PTSD-SS scores than other groups. The non-PTSD group had a higher health-related quality-of-life score compared with the full and partial PTSD groups in the domains of physical function, role-physical, bodily pain, general health, vitality, social functioning, role-emotional, and mental health. In addition, the occurrence of PTSD was related to a poorer quality of life. The occurrence of PTSD was common in living donors after pediatric liver transplantation. Those with a lower educational status, who were donors to their children, were in the first 6 months after transplant, or were involved in transplants where the recipients had severe complications were most likely to experience PTSD. Post-traumatic stress symptom severity was significantly associated with a poorer quality of life after transplant.