Open AccessDifferences in treatment outcomes between ultrasound-guided percutaneous microwave ablation and endoscopic thyroidectomy for patients with papillary thyroid microcarcinoma
Author(s) -
Yan Shen,
Miao Liu,
Jie He,
Shu Wu,
Yonglin Wan,
Jun Ding,
Xiaoyan Cai,
Xiaohong Fu
Publication year - 2019
Publication title -
medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.59
H-Index - 148
eISSN - 1536-5964
pISSN - 0025-7974
DOI - 10.1097/md.0000000000013953
Subject(s) - medicine , thyroidectomy , microwave ablation , percutaneous , radiology , randomized controlled trial , observational study , general surgery , ablation , surgery , thyroid
Background: The differences in treatment outcomes between ultrasound (US)-guided percutaneous microwave ablation (PMWA) and endoscopic thyroidectomy for patients with papillary thyroid microcarcinoma (PTMC) remains unknown. Methods: An electronic search will be performed for randomized controlled trials or observational studies that reported recurrence and mortality rates in PTMC patients with US-guided PMWA or endoscopic thyroidectomy. Hazard ratios with their 95% confidence intervals will be calculated using fixed- or random-effects models according to heterogeneity. Results: This study will present the differences in treatment outcomes between US-guided PMWA and endoscopic thyroidectomy for patients with PTMC by pooling the results of individual studies. Conclusion: The results of this study would provide vigorous evidence in this issue and offer the guidance to both clinical decision-making and future research. Ethics and dissemination: Ethical approval is not applicable for this study. PROSPERO registration number: CRD42018112320.