
Chinese herbal medicine for recurrent aphthous stomatitis: a protocol for systematic review and meta-analysis
Author(s) -
Ying Zhang,
Kwan-him Ng,
Chih-Yu Kuo,
Dongjie Wu
Publication year - 2018
Publication title -
medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.59
H-Index - 148
eISSN - 1536-5964
pISSN - 0025-7974
DOI - 10.1097/md.0000000000013681
Subject(s) - medicine , cochrane library , recurrent aphthous stomatitis , stomatitis , oral medicine , medline , meta analysis , alternative medicine , randomized controlled trial , systematic review , traditional chinese medicine , protocol (science) , traditional medicine , cochrane collaboration , dermatology , family medicine , dentistry , pathology , political science , law
Background: Recurrent aphthous stomatitis (RAS) is the most frequent form of oral ulceration, characterized by recurrent oral mucosal ulceration in an otherwise healthy individual. This study was designed to evaluate the efficacy and safety of Chinese herbal medicine for recurrent aphthous stomatitis. Methods: Five databases will be searched from inception to date, including PubMed, Cochrane Library, EMBASE,CNKI, and CBM. The researchers will comprehensively screen clinical randomized trials of Chinese herbal medicine for recurrent aphthous stomatitis. The review will be conducted by 2 independent authors without time and language limitation. The risk of bias will be assessed by the Cochrane risk of bias tool. Results: Ethical approval is not required because this study is based on published papers. After peer-review, the study will be disseminated in scientific journals and conferences. Conclusion: This systematic review will provide evidence for the efficacy and safety of Chinese medicine for recurrent aphthous stomatitis. PROSPERO registration: CRD42018111955.