Open AccessCyclosporin A-related cerebral venous sinus thrombosis
Author(s) -
Fei Gao,
Jun Zhang,
Fang Wang,
Xiaoyan Xin,
Dujuan Sha
Publication year - 2018
Publication title -
medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.59
H-Index - 148
eISSN - 1536-5964
pISSN - 0025-7974
DOI - 10.1097/md.0000000000011642
Subject(s) - medicine , venous thrombosis , cerebral venous sinus thrombosis , thrombosis , intracranial thrombosis , cardiology
Rationale: Cerebral venous sinus thrombosis (CVST) is a complex life-threatening condition, and its etiology is not well understood. Although oral cyclosporin A is not a common cause of the symptoms related to CVST, there is limited information available. Patient concerns: In this study, we report a rare case of CVST in a 44-year-old woman with aplastic anemia, who was given cyclosporin A orally for a period of 18 months. She had experienced a headache for 20 days. Diagnoses: The patient was diagnosed with CVST by computed tomography venography. Interventions: Low molecular heparin (enoxaparin, 4000 AXaIU, subcutaneous injection, once every 12 hours) was administered for anticoagulation. Outcomes: The patient developed no recurrence of thrombosis during the 13-month follow-up period. Lessons: Clinicians should be aware of the possibility of CVST when patients are treated with cyclosporin A and have symptoms such as headaches.