Open AccessStatin in the treatment of patients with myocardial infarction
Author(s) -
Xue Han,
Yi Zhang,
Lifang Yin,
Lin Zhang,
Yue Wang,
Hongshan Zhang,
Bo Li
Publication year - 2018
Publication title -
medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.59
H-Index - 148
eISSN - 1536-5964
pISSN - 0025-7974
DOI - 10.1097/md.0000000000010167
Subject(s) - medicine , statin , myocardial infarction , odds ratio , meta analysis , confidence interval , randomized controlled trial , medline , cardiology , political science , law
The purpose of this meta-analysis is to investigate whether statin is a key therapy for myocardial infarction (MI) by comparing all randomized controlled trials that appraised the effects of statin on risk of MI. Pubmed, Embase, and Medline databases (up to December 2016) were used to search all related articles. Using the data from 18 available publications, we examined the efficacy in treating or reducing the risk of MI by using random-effects models of odds ratio (OR) comparing the highest with the lowest category. Statins have demonstrated efficacy in treating or reducing the risk of MI (OR = 0.73, 95% confidence interval = 0.58–0.93, P = .010). This meta-analysis suggests that statin have light efficacy in treating or reducing the risk of MI patients.