Open AccessEffects of Shenmai injection on the values of CO, SV, and EF in patients undergoing off-pump coronary artery bypass graft
Author(s) -
Qingxue Liu,
Haiyan Wu,
Jianjuan Wang,
Ximing Li
Publication year - 2018
Publication title -
medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.59
H-Index - 148
eISSN - 1536-5964
pISSN - 0025-7974
DOI - 10.1097/md.0000000000010085
Subject(s) - medicine , cardiology , artery , coronary artery bypass surgery
Background: To explore the effects of Shenmai (SM) injection on the values of cardiac output (CO), stroke volume (SV), and the ejection fraction (EF) in patients treated with off-pump coronary artery bypass graft (OPCABG). Methods: Forty patients undergoing OPCABG were randomly divided into SM group (n = 20) and the 5% glucose (G) group (n = 20). The control liquids were injected from the beginning of the operation to the start of coronary artery bypass graft (CABG). The values of CO, SV, and EF before induction (t 1 ), at the beginning of operation (t 2 ), 30 minutes after the start of operation (t 3 ), at the beginning of coronary artery bypass graft (t 4 ), at the end of coronary artery bypass graft (CABG) (t 5 ), and at the end of operation (t 6 ) were recorded. Results: The values of CO, SV, and EF in the patients of SM group at t 3 to t 6 were found to be significantly higher than those at t 1 ( P < .05). The values of CO, SV, and EF in the patients of G group were found to be increased at t 5 and t 6 ( P < .05). At t 3 and t 4 , the values of CO, SV, and EF in SM group were significantly higher than those in the G group ( P < .05). Conclusion: In patients with OPCABG, the infusion of SM injection can effectively increase the values of CO, SV, and EF and increase the safety of anesthesia management.