Open AccessUltrasonographic manifestations of a rare granular cell tumor of the accessory breast
Author(s) -
Haotian Liu,
Meiying Tao,
Haiyan Ding,
Peipei Zhang
Publication year - 2018
Publication title -
medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.59
H-Index - 148
eISSN - 1536-5964
pISSN - 0025-7974
DOI - 10.1097/md.0000000000009462
Subject(s) - medicine , breast cancer , axillary lymph nodes , differential diagnosis , granular cell tumor , breast ultrasound , radiology , cd68 , lymph node , pathology , immunohistochemistry , cancer , mammography
Rationale: The ultrasound manifestations of granular cell tumor (GCT) is a consequence of the histopathological characteristic of the tumor and can be distinguished from breast cancer. Patient concerns: A GCT is a rare, benign, hyperplasia-based lesion. Approximately 1% to 2% of GCTs are malignant. About 5% to15% of the cases occur in the breast, and it is relatively rare in the axillary accessory breast. There are no effective preventive measures for GCTs, early detection combined with a thorough and wide complete resection of the tumor remains the best treatment for a favorable outcome. Diagnoses: A 45-year-old female patient with an axillary mass of more than 3 months duration was examined through physical examination, color Doppler ultrasound and postoperative pathology. Interventions: A provisional diagnosis of left axillary lymph node enlargement was made and necessary investigations were advised. Outcomes: A differential diagnosis of accessory breast in the left arm pit, possibly malignant, or a solid mass in the left arm pit secondary to chronic inflammation. Postoperative pathology: GCT of axillary accessory breast, with tumor-free margins. Immunohistochemical staining showed strong S-100 positivity, CD68 positivity, and negative periodic acid-Schiff staining. Lessons: The ultrasound examination can detect GCT mass in the breast/accessory breast and is not easy to misdiagnosis.