Open AccessAntiangiogenic therapy for primitive neuroectodermal tumor with thalidomide
Author(s) -
Qing Li,
Yong Liu,
Yang Yu
Publication year - 2017
Publication title -
medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.59
H-Index - 148
eISSN - 1536-5964
pISSN - 0025-7974
DOI - 10.1097/md.0000000000009272
Subject(s) - medicine , thalidomide , primitive neuroectodermal tumor , radiation therapy , chemotherapy , sarcoma , neuroectodermal tumor , lung , soft tissue , surgery , oncology , pathology , multiple myeloma
Rationale: Peripheral primitive neuroectodermal tumor (PNET) is a kind of small round cell tumor derived from primitive neuroectodermal tumor. Patient concerns: PNET is a highly malignant tumor that is subordinated to Ewing sarcoma. It occurs predominantly in soft tissue and bone and rarely in the bronchi and lung. Traditional surgery, radiotherapy, and chemotherapy are used for the treatment of PNET, but are usually ineffective. Diagnoses: There was a rare case of a 17 year-old man diagnoses with primary pulmonary PNET. Interventions: The patient was treated by the remedy treatment with thalidomide after the poor effect of conventional radiotherapy and chemotherapy. Outcomes: The patient survived without disease progression for 15 months and was in stable condition. Lessons: Thalidomide provides a choice for maintenance therapy in PNET.