Open AccessSimultaneous endoscopic submucosal dissection for multiple early gastric cancers in a low volume center
Author(s) -
Zhao-Sheng Chen,
Xi-Feng Jin,
Honglei Wu,
Jianqiang Guo
Publication year - 2017
Publication title -
medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.59
H-Index - 148
eISSN - 1536-5964
pISSN - 0025-7974
DOI - 10.1097/md.0000000000007745
Subject(s) - medicine , endoscopic submucosal dissection , surgery , stomach , resection , cancer , incidence (geometry) , single center , retrospective cohort study , dissection (medical) , endoscopic mucosal resection , gastroenterology , physics , optics
The aim of the study is to evaluate the safety and efficacy of simultaneous endoscopic submucosal dissection (ESD) for multiple early gastric cancers. A total of 70 solitary early gastric cancers from 70 patients and 20 multiple early gastric cancers from 10 patients were included in this retrospective study. The curative resection rate, en bloc resection rate, procedure-related complications, and local recurrence were compared between the 2 groups. There was no statistical difference in the rate of complete resection, en bloc resection, and curative resection between the 2 groups ( P > .05). No significant difference was found with respect to the occurrence of postoperative bleeding ( P > .05). Procedure time was significantly longer in the simultaneous group than that in the single group (87.6 ± 25.1 min vs 54.6 ± 22.0 min, P = .004). The overall incidence of synchronous early gastric cancer was 7.5%. Simultaneous ESD for multiple early gastric cancers is a safe and feasible choice in low-volume hospital. The entire stomach should be examined meticulously during and after ESD. Larger randomized studies are needed to validate our results.