Open AccessUse of sugammadex in a patient with progressive muscular atrophy and in a patient with amyotrophic lateral sclerosis
Author(s) -
Jae Hwa Yoo,
Soon Im Kim,
Sun Young Park,
Mi Roung Jun,
Yong Eun Kim,
Hyoung June Kim
Publication year - 2017
Publication title -
medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.59
H-Index - 148
eISSN - 1536-5964
pISSN - 0025-7974
DOI - 10.1097/md.0000000000007098
Subject(s) - sugammadex , medicine , rocuronium , remifentanil , amyotrophic lateral sclerosis , anesthesia , neuromuscular blockade , propofol , progressive muscular atrophy , surgery , atrophy , disease
We herein present 2 cases involving the combination of rocuronium and sugammadex in patients with motor neuron disease. The patients were a 54-year-old man with progressive muscular atrophy who underwent removal of internal fixators in the arm and leg, and a 66-year-old woman with amyotrophic lateral sclerosis who underwent skin grafting in the left lower leg. General anesthesia was induced with propofol, rocuronium, and remifentanil and maintained with desflurane and remifentanil. At the end of the surgical procedure, we administered sugammadex. Three or 4 minutes after administration of sugammadex, the patients began to breathe spontaneously and were extubated without complications. Conclusion: Sugammadex can be used successfully to reverse neuromuscular blockade in patients with motor neuron disease.