Open AccessAnalyses and treatments of postoperative nasal complications after endonasal transsphenoidal resection of pituitary neoplasms
Author(s) -
You Cheng,
Fei Xue,
Tianyou Wang,
Junfeng Ji,
Wei Chen,
Zhiyi Wang,
Lang Xu,
Chun-Hua Hang,
Xinfeng Liu
Publication year - 2017
Publication title -
medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.59
H-Index - 148
eISSN - 1536-5964
pISSN - 0025-7974
DOI - 10.1097/md.0000000000006614
Subject(s) - medicine , nasal cavity , surgery , nasal administration , nasal septum , rhinorrhea , endoscopic endonasal surgery , transsphenoidal surgery , mucous membrane of nose , sinusitis , perforation , sinus (botany) , nasal lavage , pituitary tumors , nose , pituitary adenoma , pathology , adenoma , skull , punching , materials science , botany , biology , genus , immunology , metallurgy
In this study, we analyze and discuss the treatments of postoperative nasal complications after endonasal transsphenoidal resection of pituitary neoplasms (PNs). We performed 129 endonasal transsphenoidal resections of PNs and analyzed and treated cases with nasal complications. After endonasal transsphenoidal resection of PNs, there were 26 cases of postoperative nasal complications (20.1%), including nasal hemorrhage (4.8%), cerebrospinal fluid rhinorrhea (6.9%), sphenoid sinusitis (2.3%), atrophic rhinitis (1.6%), olfactory disorder (1.6%), perforation of nasal septum (0.8%), and nasal adhesion (2.3%). All patients clinically recovered after therapy, which included treatment of the cavity through nasal endoscopy, intranasal corticosteroids, and nasal irrigation. We propose that regular nasal endoscopic review, specific nasal medications, and regular nasal irrigation can effectively clear nasal mucosal hyperemia-induced edema and nasal/nasoantral secretions, as well as promote regeneration of nasal mucosa, prevent nasal adhesion, maintain the sinus cavity drainage, and accelerate the recovery of the physiological function of the paranasal sinus. Timely treatment of patients with nasal complications after endonasal transsphenoidal resections of PNs could greatly relieve the clinical symptoms. Nasal cleaning is very beneficial to patients after surgery recovery.