Open AccessThe efficacy of periarticular drug infiltration for postoperative pain after total hip arthroplasty
Author(s) -
Yanyang Wang,
Fuqiang Gao,
Wei Sun,
Bailiang Wang,
Wanshou Guo,
Zirong Li
Publication year - 2017
Publication title -
medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.59
H-Index - 148
eISSN - 1536-5964
pISSN - 0025-7974
DOI - 10.1097/md.0000000000006401
Subject(s) - medicine , nausea , cochrane library , placebo , randomized controlled trial , arthroplasty , opioid , meta analysis , vomiting , medline , anesthesia , surgery , alternative medicine , receptor , pathology , political science , law
Background: The ability of intraoperative periarticular drug infiltration (PDI) to control pain after total hip arthroplasty (THA) has been studied for many times, but it still remains controversial. Therefore, we undertook a meta-analysis to evaluate the efficacy and safety of PDI on postoperative pain after THA. Methods: Databases, including Pubmed, Medline, Embase, Web of Science, and Cochrane library, were searched to identify randomized controlled trials concerning PDI for pain management in patients undergoing THA. The primary outcomes included pain score with rest or activity and opioid consumption. Secondary outcomes were length of hospital stay and complications (nausea or vomiting). Results: A total of 666 THA patients from 8 randomized controlled trials were subjected to meta-analysis. The results showed that the PDI group had better pain relief, less opioid consumption, and less length of hospital, when compared with the placebo group ( P < 0.05). No significant differences were observed in regard to visual analog score with activity and complications between the 2 groups. Conclusion: PDI may be recommended for the pain management after THA. However, due to the variations in the included studies, additional studies are still needed to validate these conclusions.