Open AccessCherubism With Bilateral Mandible and Maxilla Involvement
Author(s) -
Zou Yu,
Miao Zhai,
Wei Gan,
Hong Zhang,
Yuefei Zhou,
Hong Ling Wen
Publication year - 2015
Publication title -
medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.59
H-Index - 148
eISSN - 1536-5964
pISSN - 0025-7974
DOI - 10.1097/md.0000000000002120
Subject(s) - cherubism , medicine , maxilla , mandible (arthropod mouthpart) , osteochondrodysplasia , giant cell , radiology , anatomy , pathology , botany , biology , genus
Cherubism is a rare, nonneoplastic, self-limiting fibro-osseous that occurs in children. Affected children usually appear normal at birth. Lesions are characterized by the replacement of bone with fibrovascular tissue containing many multinucleated giant cells. Most studies have reported cherubism to be familial and with bilateral involvement of the mandibles. The authors describe a nonfamilial case of cherubism, involving both the mandible and the maxilla, in a 4-year-old female child with slowly enlarging, painless, symmetrical swelling of both cheeks. Cherubism is a rare disease that is usually limited to the mandible, but the maxilla may be involved. Computed tomography scan and biopsy are helpful for early diagnosis.