Open AccessMolecular profiling in sarcoidosis
Author(s) -
N. Arger,
Brian P. O’Connor,
Laura L. Koth
Publication year - 2020
Publication title -
current opinion in pulmonary medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.937
H-Index - 75
eISSN - 1531-6971
pISSN - 1070-5287
DOI - 10.1097/mcp.0000000000000716
Subject(s) - sarcoidosis , medicine , phenotype , disease , transcriptome , gene expression profiling , immunology , systemic disease , clinical phenotype , computational biology , bioinformatics , gene , pathology , gene expression , genetics , biology
Sarcoidosis is a systemic disease characterized by granulomatous inflammation of unknown cause. There is extensive heterogeneity between patients with respect to the number and types of organs involved, disease course, and response to therapy. Recent research in the field has leveraged 'omics' techniques such as transcriptomics to identify important 'molecular profiles' in the disease. These tools may help in identifying clinically useful biomarkers and targets for therapy.