Open AccessMetabolic aspects of muscle wasting during critical illness
Author(s) -
Rob J. J. van Gassel,
Michelle R. Baggerman,
Marcel C. G. van de Poll
Publication year - 2020
Publication title -
current opinion in clinical nutrition and metabolic care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.21
H-Index - 111
eISSN - 1473-6519
pISSN - 1363-1950
DOI - 10.1097/mco.0000000000000628
Subject(s) - wasting , critical illness , medicine , intensive care medicine , critically ill
Skeletal muscle wasting during critical illness is the result of disturbed metabolism. No proven effective interventions targeting skeletal muscle mass and function during critical illness currently exist. This review summarizes recent advances regarding the complexity of metabolic factors involved and the challenge of establishing the clinical effects of metabolic interventions targeting the muscle.