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Application and Validation of a New Histologic Staging and Grading System for Primary Biliary Cirrhosis
Author(s) -
Kenichi Harada,
Maylee Hsu,
Hiroko Ikeda,
Mikio Zeniya,
Yasuni Nakanuma
Publication year - 2012
Publication title -
journal of clinical gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.141
H-Index - 112
eISSN - 1539-2031
pISSN - 0192-0790
DOI - 10.1097/mcg.0b013e31827234e4
Subject(s) - medicine , cirrhosis , grading (engineering) , primary biliary cirrhosis , fibrosis , gastroenterology , liver biopsy , bile duct , cholestasis , biopsy , hepatic fibrosis , pathology , chronic hepatitis , chronic liver disease , immunology , civil engineering , engineering , virus
We proposed a new grading and staging system for primary biliary cirrhosis (PBC), which takes into account the degree of both chronic cholangitis activity (CA) and hepatitic activity (HA) for grading disease activity and that of fibrosis, bile duct loss, and chronic cholestasis for staging. In this study, we validated our new system.

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