Open AccessPlacebo Response Rates in Acupuncture Therapy Trials for Functional Dyspepsia
Author(s) -
Jie Liu,
Gengqing Song,
Yizhou Huang,
Chaolan Lv,
Ying Wang,
Dandan Wu,
Chenyu Sun,
Jian Meng,
Yue Yu
Publication year - 2022
Publication title -
journal of clinical gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.141
H-Index - 112
eISSN - 1539-2031
pISSN - 0192-0790
DOI - 10.1097/mcg.0000000000001679
Subject(s) - medicine , jadad scale , placebo , acupuncture , strictly standardized mean difference , randomized controlled trial , confidence interval , meta analysis , physical therapy , electroacupuncture , publication bias , cochrane library , clinical trial , medline , alternative medicine , pathology , political science , law
Functional dyspepsia (FD) is a functional digestive disease with limited management selection. Previous studies revealed that acupuncture therapy is effective for FD. However, because sham controls were not implemented in most clinical trials following acupuncture therapy, it is difficult to differentiate overall treatment responses from placebo. This study aims to quantify placebo responses in clinical trials in which FD patients received sham manual acupuncture (MA) and sham electroacupuncture (EA).