Open AccessCirculating biomarkers to assess cardiovascular function in critically ill
Author(s) -
Dirk van Lier,
Peter Pickkers
Publication year - 2021
Publication title -
current opinion in critical care, with evaluated medline/current opinion in critical care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.212
H-Index - 88
eISSN - 1080-8183
pISSN - 1070-5295
DOI - 10.1097/mcc.0000000000000829
Subject(s) - medicine , intensive care medicine , personalized medicine , circulatory system , bioinformatics , adrenomedullin , biology , receptor
Circulatory shock is one of the most common reasons for ICU admission. Mortality rates in excess of 40% necessitate the rapid identification of high-risk patients, as well as the early assessment of effects of initiated treatments. There is an unmet medical need for circulating biomarkers that may improve patient stratification, predict responses to treatment interventions and may even be a target for novel therapies, enabling a better biological rationale to personalize therapy.