Open AccessHow much oxygen for the injured brain – can invasive parenchymal catheters help?
Author(s) -
Matthew R Leach,
Lori Shutter
Publication year - 2021
Publication title -
current opinion in critical care, with evaluated medline/current opinion in critical care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.212
H-Index - 88
eISSN - 1080-8183
pISSN - 1070-5295
DOI - 10.1097/mcc.0000000000000810
Subject(s) - medicine , traumatic brain injury , intensive care medicine , clinical trial , intracranial pressure , anesthesia , psychiatry
Each year in the United States there are over 2.5 million visits to emergency departments for traumatic brain injury (TBI), 300,000 hospitalizations, and 50,000 deaths. TBI initiates a complex cascade of events which can lead to significant secondary brain damage. Great interest exists in directly measuring cerebral oxygen delivery and demand after TBI to prevent this secondary injury. Several invasive, catheter-based devices are now available which directly monitor the partial pressure of oxygen in brain tissue (PbtO2), yet significant equipoise exists regarding their clinical use in severe TBI.