Open AccessMucormycosis-associated intracranial hemorrhage
Author(s) -
Javier Muñoz,
Amy Hughes,
Yue Guo
Publication year - 2013
Publication title -
blood coagulation and fibrinolysis
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.376
H-Index - 71
eISSN - 1473-5733
pISSN - 0957-5235
DOI - 10.1097/mbc.0b013e32835a72df
Subject(s) - mucormycosis , medicine , aplastic anemia , intracranial hemorrhages , plasmacytosis , surgery , bone marrow , subarachnoid hemorrhage
Rhinoorbitocerebral mucormycosis is a devastating infection being increasingly recognized in immunocompromised hosts and carries poor prognosis. Early recognition and treatment are critical in order to improve clinical outcomes and decrease the development of complications. Fatal cerebral infarctions have been described in patients with rhinoorbitocerebral mucormycosis, likely due to the thrombotic occlusion of the affected blood vessels directly invaded by this aggressive mycotic infection. We report a patient that presented with aplastic anemia, subsequently complicated by systemic mucormycosis, which generated reactive plasmacytosis, and developed intracranial infarction and hemorrhage.