Open AccessFirst-in-man Implantation of a Cardiac Microcurrent Device for Chronic Systolic Heart Failure
Author(s) -
Jan D. Schmitto,
L. Christian Napp,
Silvia Mariani,
Jasmin S. Hanke,
Tong Li,
Jens VogelClaussen,
K. Brandes,
Peter Göttel,
Johannes Müller,
G. Dogan,
Johann Bauersachs,
Axel Haverich
Publication year - 2022
Publication title -
asaio journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.961
H-Index - 66
eISSN - 1538-943X
pISSN - 1058-2916
DOI - 10.1097/mat.0000000000001537
Subject(s) - medicine , ejection fraction , heart failure , contractility , cardiology , thoracotomy , cardiomyopathy , dilated cardiomyopathy
Current therapies significantly improve survival and clinical endpoints in patients suffering from chronic heart failure with reduced ejection fraction (HFrEF), but most are not sufficient to reverse adverse remodeling and improve myocardial contractility. Herein, we report the first-in-man experience with a novel fully implantable device for cardiac electrical microcurrent (C-MIC) application. A 79-year-old man suffering from HFrEF (dilated cardiomyopathy, NYHA class III, left ventricular ejection fraction 30%) successfully underwent implantation of the C-MIC device through left anterolateral thoracotomy. At 30-day follow-up, no device-related complications were observed, demonstrating feasibility of C-MIC implantation in a patient suffering from HFrEF.