Open AccessThe Effects of Hemodynamic Unloading in African Americans Implanted with Left Ventricular Assist Devices
Author(s) -
David M. Tehrani,
Daniel Rodgers,
Sirtaz Adatya,
Nitasha Sarswat,
J. Raikhelkar,
Gene Kim,
Gabriel Sayer,
Nir Uriel
Publication year - 2019
Publication title -
asaio journal
Language(s) - English
Resource type - Journals
eISSN - 1538-943X
pISSN - 1058-2916
DOI - 10.1097/mat.0000000000000779
Subject(s) - hemodynamics , cardiology , medicine , heart failure , diastole , cardiac output , blood pressure
We aim to evaluate the echocardiographic/hemodynamic effects of left ventricular assist devices in African American (AA) versus non-AA patients undergoing ramp speed optimization and its subsequent effect on readmissions. In 65 patients (26 AA), no differences in baseline echocardiographic/hemodynamic parameters were noted. During ramp testing, there was a significantly greater increase in cardiac output (slope: 0.29 ± 0.24 vs. 0.15 ± 0.12, p < 0.01) with more rapid decrease in left ventricular end-diastolic diameter (slope: -0.21 ± 0.14 vs. -0.13 ± 0.07 L/min, p < 0.01) in the AA group. AAs had higher all-cause, but similar heart failure readmission rate as compared with the non-AA group.