
IgG Myeloma Presenting as a Large Mediastinal Mass and Pleural Effusion
Author(s) -
Erin E. Wetherbee,
H. Erhan Dincer
Publication year - 2012
Publication title -
journal of bronchology and interventional pulmonology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.648
H-Index - 33
eISSN - 1944-6586
pISSN - 1948-8270
DOI - 10.1097/lbr.0b013e31823fcc5b
Subject(s) - medicine , plasma cell dyscrasia , plasmacytoma , mediastinal mass , pleural effusion , multiple myeloma , extramedullary plasmacytoma , mediastinal lymphadenopathy , dyscrasia , plasma cell , radiology , pathology , biopsy , antibody , immunology , immunoglobulin light chain
Plasmacytoma, a rare form of plasma cell dyscrasia, refers to a neoplastic proliferation of plasma cells. Although the upper aerodigestive tract is the most common site for extramedullary plasmacytoma, mediastinal and pleural involvement is extremely rare. We report the case of a patient who presented with a large mediastinal mass and pleural effusion. Diagnosis was challenging and subsequently made as mediastinal extramedullary plasmacytoma with simultaneous myelomatous pleural effusion. Further investigations revealed multiple myeloma.