Open AccessCombining Autofluorescence and Narrow Band Imaging With Image Analysis in the Evaluation of Preneoplastic Lesions in the Bronchus and Larynx
Author(s) -
Phan Nguyen,
Olivier Salvado,
Ian Brent Masters,
Camile S. Farah,
David Fielding
Publication year - 2010
Publication title -
journal of bronchology and interventional pulmonology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.648
H-Index - 33
eISSN - 1944-6586
pISSN - 1948-8270
DOI - 10.1097/lbr.0b013e3181da2ca8
Subject(s) - medicine , narrow band imaging , larynx , autofluorescence , bronchus , radiology , laryngeal neoplasm , bronchoscopy , pathology , endoscopy , anatomy , respiratory disease , optics , lung , fluorescence , physics
Autofluorescence (AF) techniques improve the diagnostic yield of white light inspection for preneoplastic lesions in the bronchus and head and neck region. Although highly sensitive, AF has poor specificity, particularly in situations where there have been earlier biopsies or treatments such as radiotherapy. Narrow band imaging (NBI) is a newer imaging technique that enhances the early abnormal angiogenesis seen in preneoplastic lesions. NBI has higher specificity when compared with AF. We aimed to combine these imaging modalities, using AF as an effective screening tool and NBI to confirm AF findings. We also used computer-assisted image analysis techniques to give objective confirmation to our visual inspection.