Open AccessPeripheral T-cell Lymphoma With Endobronchial Involvement
Author(s) -
Gustavo Ferrer,
Guillermo Gutiérrez,
Arnold M. Schwartz,
Morgan D. Delaney
Publication year - 2010
Publication title -
journal of bronchology and interventional pulmonology
Language(s) - Uncategorized
Resource type - Journals
eISSN - 1944-6586
pISSN - 1948-8270
DOI - 10.1097/lbr.0b013e3181da2a60
Subject(s) - medicine , peripheral t cell lymphoma , lymphoma , pathology , peripheral , infiltration (hvac) , lesion , lymphoproliferative disorders , cutaneous t cell lymphoma , t cell , mycosis fungoides , immunology , physics , immune system , thermodynamics
Peripheral T-cell lymphoma unspecified (PTCL-U) is a lymphoproliferative disorder characterized by localized malignant T-lymphocyte infiltration of the skin. PTCL-U is a rare disease of the elderly with a low 5-year survival rate (16%). The skin is affected variably with localized plaques, nodules, or tumors. The lungs are involved in less than 10% of the cases. Nodules, masses, or mass-like consolidations are the most common pulmonary manifestations of PTCL-U. Pulmonary involvement by PTCL-U is associated with a poor prognosis. We report a case of PTCL-U presenting as an endobronchial and a parenchymal lesion before the skin manifestations. To our knowledge, this is the first report in the literature of pulmonary involvement preceding the dermatological manifestation of PTCL-U.