Open AccessAssessment of Chemosensitivity-related Aberrant Methylation of Nonsmall Cell Lung Cancer by EBUS-TBNA
Author(s) -
Takahiro Nakajima,
Kazuhiro Yasufuku,
Makoto Suzuki,
Taiki Fujiwara,
Kiyoshi Shibuya,
Yuichi Takiguchi,
Kenzo Hiroshima,
Hideki Kimura,
Ichiro Yoshino
Publication year - 2009
Publication title -
journal of bronchology and interventional pulmonology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.648
H-Index - 33
eISSN - 1944-6586
pISSN - 1948-8270
DOI - 10.1097/lbr.0b013e318195d930
Subject(s) - medicine , lung cancer , methylation , dna methylation , chemotherapy , adenocarcinoma , cancer research , oncology , biopsy , carcinoma , pathology , cancer , lymph node , gene , gene expression , biology , biochemistry
Multigene aberrant methylation profiling may predict response to chemotherapy in lung cancer. The purpose of this study was to analyze the feasibility of detecting aberrant methylation in biopsy samples obtained by endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA).