Open AccessPhotodynamic Therapy for Bronchial Microscopic Residual Disease After Resection in Lung Cancer
Author(s) -
Hiren J. Mehta,
Abhishek Biswas,
Sebastián Fernández-Bussy,
M. Pipkin,
T. Machuca,
Michael A. Jantz
Publication year - 2019
Publication title -
journal of bronchology and interventional pulmonology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.648
H-Index - 33
eISSN - 1944-6586
pISSN - 1948-8270
DOI - 10.1097/lbr.0000000000000510
Subject(s) - medicine , lung cancer , stage (stratigraphy) , surgery , photodynamic therapy , radiation therapy , carcinoma in situ , cancer , carcinoma , radiology , biology , paleontology , chemistry , organic chemistry
The goal of lung cancer surgery is a complete tumor resection (R0 resection) with clear margins. 4% to 5% of resections have microscopic residual disease associated with worse prognosis. Definitive management is resection of residual tumor, which may not be tolerated by many patients, and definitive management is not well studied in these patients. We treated patients with stage I cancer and bronchial mucosal residual disease (MRD) with bronchoscopic photodynamic therapy (PDT).