Open AccessUnusual Triad of Obstructive Sleep Apnea, Uncontrolled Hypertension, and Severe Hypokalemia Due to Ectopic Adrenocorticotropic Secretion
Author(s) -
Sindhaghatta Venkatram,
Trupti Vakde,
Kanthi Rekha Badipatla,
Masooma Niazi,
Gilda DiazFuentes
Publication year - 2014
Publication title -
journal of bronchology and interventional pulmonology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.648
H-Index - 33
eISSN - 1944-6586
pISSN - 1948-8270
DOI - 10.1097/lbr.0000000000000060
Subject(s) - medicine , hypokalemia , adrenocorticotropic hormone , obstructive sleep apnea , gastroenterology , endocrinology , hormone
Ectopic adrenocorticotropic hormone secretion is responsible for 12% to 17% of all cases of the Cushing syndrome. One of the most commonly described causes of ectopic adrenocorticotropic hormone secretion is small cell carcinoma of the lung. A rare cause includes a functioning neuroendocrine tumor traditionally known as carcinoids that account for 5% of all mediastinal tumors. To our knowledge, all reported cases of mediastinal carcinoids are thymic in origin and only a minority of those is functional. We present a male patient with hypertension, obstructive sleep apnea, and acid-base disorder, in whom further investigation revealed an anterior mediastinal mass and Cushing syndrome.