Open AccessDiagnostic Test Characteristics of Ultrasound Based Hydronephrosis in Identifying Low Kidney Function in Young Patients with Spina Bifida: A Retrospective Cohort Study
Author(s) -
David I. Chu,
Lauren C. Balmert,
Liqi Chen,
Cameron Arkin,
Theresa Meyer,
Ilina Rosoklija,
Diana K. Bowen,
Kavita S. Hodgkins,
Robin Bowman,
Earl Y. Cheng,
Elizabeth B. Yerkes,
Tamara Isakova
Publication year - 2021
Publication title -
the journal of urology/the journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.402
H-Index - 256
eISSN - 1527-3792
pISSN - 0022-5347
DOI - 10.1097/ju.0000000000001411
Subject(s) - medicine , biostatistics , spina bifida , retrospective cohort study , family medicine , public health , pediatrics , surgery , nursing
Kidney dysfunction in spina bifida is usually detected by low estimated glomerular filtration rate or ultrasound based hydronephrosis. We assessed the diagnostic test characteristics of hydronephrosis for detecting low estimated glomerular filtration rate, hypothesizing that hydronephrosis has low sensitivity compared to cystatin C based estimated glomerular filtration rate.