Open AccessPersonalized Risks of Over Diagnosis for Screen Detected Prostate Cancer Incorporating Patient Comorbidities: Estimation and Communication
Author(s) -
Roman Gulati,
Sarah P. Psutka,
Ruth Etzioni
Publication year - 2019
Publication title -
the journal of urology/the journal of urology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.402
H-Index - 256
eISSN - 1527-3792
pISSN - 0022-5347
DOI - 10.1097/ju.0000000000000346
Subject(s) - medicine , comorbidity , prostate cancer , prostate specific antigen , logistic regression , overdiagnosis , cancer , calculator , population , intensive care medicine , environmental health , computer science , operating system
Shared patient-physician decision making regarding the treatment of prostate cancer detected by prostate specific antigen screening involves a complex calculus weighing cancer risk and patient life expectancy. We sought to quantify these competing risks using the probability that the cancer was over diagnosed, ie would not have been clinically diagnosed (diagnosed without screening) during the remaining lifetime of the patient.