Open AccessOvercoming Barriers to Progress in Exercise Genomics
Author(s) -
Claude Bouchard
Publication year - 2011
Publication title -
exercise and sport sciences reviews
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.945
H-Index - 99
eISSN - 1538-3008
pISSN - 0091-6331
DOI - 10.1097/jes.0b013e31822643f6
Subject(s) - genomics , functional genomics , computational biology , genome wide association study , genome , biology , data science , genetics , computer science , genotype , gene , single nucleotide polymorphism
This commentary focuses on the issues of statistical power, the usefulness of hypothesis-free approaches such as in genome-wide association explorations, the necessity of expanding the research beyond common DNA variants, the advantage of combining transcriptomics with genomics, and the complexities inherent to the search for links between genotype and phenotype in exercise genomics research.