Open AccessThe Acute Stress-Induced Immunoenhancement Hypothesis
Author(s) -
Kate M. Edwards,
Victoria E. Burns,
Douglas Carroll,
Mark T. Drayson,
Christopher Ring
Publication year - 2007
Publication title -
exercise and sport sciences reviews
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.945
H-Index - 99
eISSN - 1538-3008
pISSN - 0091-6331
DOI - 10.1097/jes.0b013e3180a031bd
Subject(s) - adjuvant , immune system , innate immune system , immunology , medicine , immunity
Acute stress, such as a bout of exercise, is accepted to cause an array of immunologic changes. Recently, it has been proposed that acute stress activation of the innate immune system might be harnessed as an adjuvant to enhance immune responses to antigen challenge. This review develops the acute stress-induced immunoenhancement hypothesis and its possible role as a vaccine adjuvant.