Open AccessImpact of Selected Initial Titration Schedules on Safety and Long-Term Effectiveness of Lamotrigine for the Treatment of Mood Disorders
Author(s) -
Tomoyuki Nakamura,
Masaru Tomita,
Susumu Hirota,
Takamasa Matsunaga,
Naohisa Uchimura
Publication year - 2022
Publication title -
journal of clinical psychopharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.786
H-Index - 121
eISSN - 1533-712X
pISSN - 0271-0749
DOI - 10.1097/jcp.0000000000001557
Subject(s) - lamotrigine , mood , term (time) , mood disorders , medicine , psychiatry , epilepsy , physics , anxiety , quantum mechanics
Lamotrigine (LTG) is used for treatment of mood disorders, but it is associated with the risk of rash occurrence in the initial administration phase. Although slow titration reduces this risk, its effectiveness in the treatment of mood disorders has not been verified. The effects of titration method on the safety and effectiveness of LTG for the treatment of mood disorders were examined in this study.