Open AccessCombined Oxytocin and Cognitive Behavioral Social Skills Training for Social Function in People With Schizophrenia
Author(s) -
Robert Boyer,
Deanna L. Kelly,
Gregory P. Strauss,
James M. Gold,
Elaine Weiner,
Jennifer Zaranski,
Shuo Chen,
Frank Blatt,
Jason Holden,
Eric Granholm
Publication year - 2021
Publication title -
journal of clinical psychopharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.786
H-Index - 121
eISSN - 1533-712X
pISSN - 0271-0749
DOI - 10.1097/jcp.0000000000001397
Subject(s) - schizoaffective disorder , schizophrenia (object oriented programming) , psychosocial , prosocial behavior , psychology , social skills , oxytocin , psychological intervention , placebo , social cognition , clinical psychology , social cognitive theory , randomized controlled trial , cognition , psychiatry , medicine , developmental psychology , psychosis , alternative medicine , pathology , neuroscience
A significant proportion of people with schizophrenia are characterized by impaired ability to socially engage with others. The development of effective interventions for social functioning remains a central therapeutic challenge. Cognitive-behavioral social skills training (CBSST) has been found to improve social functioning in schizophrenia, but with only medium effect sizes. Intranasal oxytocin also has prosocial effects, but also only with modest effect sizes. This study assessed whether the addition of intranasal oxytocin to CBSST can strengthen their impact on social function.