Open AccessPolaprezinc (Zinc–l-Carnosine Complex) as an Add-on Therapy for Binge Eating Disorder and Bulimia Nervosa, and the Possible Involvement of Zinc Deficiency in These Conditions
Author(s) -
Kensaku Sakae,
Machi Suka,
Hiroyuki Yanagisawa
Publication year - 2020
Publication title -
journal of clinical psychopharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.786
H-Index - 121
eISSN - 1533-712X
pISSN - 0271-0749
DOI - 10.1097/jcp.0000000000001284
Subject(s) - bulimia nervosa , carnosine , binge eating , zinc deficiency (plant disorder) , medicine , binge eating disorder , gastroenterology , appetite , psychology , eating disorders , psychiatry , micronutrient , pathology
Zinc plays an important role in appetite regulation. L-Carnosine, an endogenous dipeptide, may also regulate eating behavior via its histaminergic and antiglutamatergic properties. Polaprezinc (zinc-L-carnosine complex) is a medication for gastric ulcers. A small case series reported successful treatment of binge eating with add-on polaprezinc.