Open AccessDeep proteogenomic investigations elucidate the NRF2 antioxidant mechanism as a major driving mechanism of lung adenocarcinoma in Asia
Author(s) -
KungHao Liang,
MongLien Wang
Publication year - 2021
Publication title -
journal of the chinese medical association
Language(s) - English
Resource type - Journals
eISSN - 1728-7731
pISSN - 1726-4901
DOI - 10.1097/jcma.0000000000000577
Subject(s) - medicine , oncology , adenocarcinoma , proportional hazards model , cohort , mechanism (biology) , lung , survival analysis , cancer research , cancer , philosophy , epistemology
Lung adenocarcinoma is a global leading cause of death. Despite modern therapeutic interventions, undesirable outcomes such as drug resistances and disease recurrence still occur. Therefore, continued investigations of disease driving mechanisms and counteracting strategies are urgently needed.