Open AccessA PRISMA-compliant meta-analysis of apolipoprotein C3 polymorphisms and nonalcoholic fatty liver disease
Author(s) -
Bing-Feng Chen,
Yeuh Chien,
Pin-Hsing Tsai,
Pang-Chung Perng,
YiPing Yang,
KuanChun Hsueh,
Chia-Hung Liu,
Yuan–Hung Wang
Publication year - 2021
Publication title -
journal of the chinese medical association
Language(s) - English
Resource type - Journals
eISSN - 1728-7731
pISSN - 1726-4901
DOI - 10.1097/jcma.0000000000000564
Subject(s) - nonalcoholic fatty liver disease , medicine , odds ratio , meta analysis , fatty liver , subgroup analysis , confidence interval , gastroenterology , allele , population , metabolic syndrome , bioinformatics , genetics , disease , gene , biology , obesity , environmental health
The relationship between apolipoprotein C3 (APOC3) gene polymorphisms and nonalcoholic fatty liver disease (NAFLD) risk has been investigated in many studies, with inconclusive findings. This meta-analysis evaluated the effect of APOC3 promoter region polymorphisms (-455T/C and -482C/T) on NAFLD susceptibility.