Open AccessDifferentiation of clinical patterns and survival outcomes of hepatocellular carcinoma on hepatitis B and nonalcoholic fatty liver disease
Author(s) -
Bou Zenn Lin,
Tsung Jung Lin,
Chun-Han Lin,
Li Ying Liao,
Ting An Chang,
Buo Jia Lu,
Kuan Yang Chen
Publication year - 2021
Publication title -
journal of the chinese medical association
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.535
H-Index - 42
eISSN - 1728-7731
pISSN - 1726-4901
DOI - 10.1097/jcma.0000000000000530
Subject(s) - medicine , hepatocellular carcinoma , nonalcoholic fatty liver disease , hbsag , gastroenterology , cirrhosis , hepatitis b , hepatitis b virus , fatty liver , liver function , liver disease , liver cancer , body mass index , disease , immunology , virus
The main etiologies of hepatocellular carcinoma (HCC) were often hepatitis B virus (HBV) or C and alcohol, rarely autoimmune and biliary diseases. Nonalcoholic fatty liver disease (NAFLD) has been an emerging role that could lead to chronic liver disease, nonalcoholic steatohepatitis, cirrhosis, and eventually HCC in recent years. The aim of our study is to investigate and compare the clinical features of HCC in patients with NAFLD and HBV, including age, gender, cirrhosis, liver function tests, largest tumor size, and cancer stage at the time of diagnosis. The survival outcome was compared between the two groups and the significant predictors of mortality were also analyzed in all patients with HCC.