Persistent liver inflammation in chronic hepatitis C patients with advanced fibrosis after direct-acting antivirals induced sustained virological response | Zendy

Yun-Cheng Hsieh | Zendy; KueiChuan Lee | Zendy; ChienWei Su | Zendy; KengHsin Lan | Zendy; Teh–Ia Huo | Zendy; Yuan-Jen Wang | Zendy; HuiChun Huang | Zendy; HanChieh Lin | Zendy; ChiJen Chu | Zendy; YiHsiang Huang | Zendy; Ming-Chih Hou | Zendy

Open Access

Persistent liver inflammation in chronic hepatitis C patients with advanced fibrosis after direct-acting antivirals induced sustained virological response

Author(s) -

Yun-Cheng Hsieh,

KueiChuan Lee,

ChienWei Su,

KengHsin Lan,

Teh–Ia Huo,

Yuan-Jen Wang,

HuiChun Huang,

HanChieh Lin,

ChiJen Chu,

YiHsiang Huang,

Ming-Chih Hou

Publication year - 2021

Publication title -

journal of the chinese medical association

Language(s) - English

Resource type - Journals

eISSN - 1728-7731

pISSN - 1726-4901

DOI - 10.1097/jcma.0000000000000517

Subject(s) - medicine , cirrhosis , gastroenterology , steatosis , inflammation , fibrosis , odds ratio , alanine aminotransferase

Direct-acting antivirals (DAA) improve sustained virological response (SVR) rates with normalization of liver enzymes in patients with hepatitis C. However, liver inflammation may persist despite virus eradication. We aimed to investigate the rate and risk factors for persistent elevated aminotransferase levels in patients with advanced fibrosis after DAA-induced SVR.

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