Open AccessRole of kisspeptin on cell proliferation and steroidogenesis in luteal cells in vitro and in vivo
Author(s) -
Chi Ming Chiang,
Han-Pang Chiu,
Chin Sung Chang,
Ya Yun Chien,
De-Shien Jong,
LeangShin Wu,
Chien Chao Chiu
Publication year - 2021
Publication title -
journal of the chinese medical association
Language(s) - English
Resource type - Journals
eISSN - 1728-7731
pISSN - 1726-4901
DOI - 10.1097/jcma.0000000000000508
Subject(s) - cholesterol side chain cleavage enzyme , kisspeptin , luteal phase , steroidogenic acute regulatory protein , in vivo , cell growth , in vitro , messenger rna , corpus luteum , endocrinology , medicine , blot , cell culture , biology , microbiology and biotechnology , receptor , ovary , hormone , biochemistry , genetics , gene
Kisspeptin (KISS1) and kisspeptin receptor (KISS1R) are essential gatekeepers of the reproductive system. The functions of KISS1 and KISS1R in corpus luteal cells remain ambiguous. The objective was to observe normal physiologic functions of corpus luteal cells in vivo and clarify the functions of KISS1 in vitro.