Open AccessCombined effects of obesity and di-(2-ethylhexyl) phthalate on testosterone levels and kisspeptin/GPR54 expression in hypothalamus and testes of male mice
Author(s) -
Lingling Zhai,
Jun Zhao,
Yunlong Bai,
Wei Wei,
Qi Sun,
Lihong Jia
Publication year - 2020
Publication title -
journal of the chinese medical association
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.535
H-Index - 42
eISSN - 1728-7731
pISSN - 1726-4901
DOI - 10.1097/jcma.0000000000000402
Subject(s) - kisspeptin , medicine , endocrinology , leptin , testosterone (patch) , hypothalamus , luteinizing hormone , hypothalamic–pituitary–gonadal axis , adipokine , hormone , phthalate , obesity , chemistry , organic chemistry
This study evaluated whether obese male mice exposed to di-(2-ethylhexyl) phthalate (DEHP) showed synergistic effects on testosterone levels and the potential underlying mechanism.