Open AccessCardiac manifestations in patients with classical or cardiac subtype of Fabry disease
Author(s) -
WeiTing Wang,
Shih Hsien Sung,
Jo Nan Liao,
Ting-Rong Hsu,
Dau Ming Niu,
Wen Chung Yu
Publication year - 2020
Publication title -
journal of the chinese medical association
Language(s) - English
Resource type - Journals
eISSN - 1728-7731
pISSN - 1726-4901
DOI - 10.1097/jcma.0000000000000379
Subject(s) - medicine , fabry disease , dyslipidemia , cohort , diabetes mellitus , cardiology , disease , gastroenterology , endocrinology
Fabry disease (FD) is an X-linked lysosomal storage disorder engendered by a deficiency of the enzyme α-galactosidase A, leading to systemic accumulation of glycolipids. Studies have reported that the cardiac subtype of FD has a later onset and minimal extracardiac involvement. However, whether the severity of cardiac involvement differs between the classic and cardiac subtypes of FD remains unclear.