Open AccessImpact of renin-angiotensin-aldosterone system activation and body weight change on N-terminal pro-B-type natriuretic peptide variation in 100-km ultramarathon runners
Author(s) -
Li Hua Li,
Wei Fong Kao,
Yu Hui Chiu,
Sen Hou,
Chen Meng,
Chorng–Kuang How
Publication year - 2020
Publication title -
journal of the chinese medical association
Language(s) - English
Resource type - Journals
eISSN - 1728-7731
pISSN - 1726-4901
DOI - 10.1097/jcma.0000000000000227
Subject(s) - medicine , aldosterone , natriuretic peptide , endocrinology , renin–angiotensin system , plasma renin activity , body weight , excretion , blood pressure , heart failure
The change in N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels follows a paradox imposed by strenuous endurance exercise. Previous reports showed significant body weight (BW) loss was common in ultramarathon runners. This study investigated whether the BW change and renin-angiotensin-aldosterone system activation contribute to exercise-induced NT-proBNP release.